{ "_id": "6a100317acfb0bcc41c7d41f", "Package": "crispRdesignR", "Type": "Package", "Title": "Guide Sequence Design for CRISPR/Cas9", "Version": "1.1.7", "Encoding": "UTF-8", "Authors@R": "c(\nperson(\"Dylan\", \"Beeber\", email = \"dylan.beeber@gmail.com\", role = c(\"aut\", \"cre\")),\nperson(\"Frederic\", \"Chain\", role = \"aut\"))", "Description": "Designs guide sequences for CRISPR/Cas9 genome editing and\nprovides information on sequence features pertinent to guide\nefficiency. Sequence features include annotated off-target\npredictions in a user-selected genome and a predicted\nefficiency score based on the model described in Doench et al.\n(2016) . Users are able to import\nadditional genomes and genome annotation files to use when\nsearching and annotating off-target hits. All guide sequences\nand off-target data can be generated through the 'R' console\nwith sgRNA_Design() or through 'crispRdesignR's' user interface\nwith crispRdesignRUI(). CRISPR (Clustered Regularly Interspaced\nShort Palindromic Repeats) and the associated protein Cas9\nrefer to a technique used in genome editing.", "URL": "", "License": "GPL-3", "RoxygenNote": "7.1.0", "Config/pak/sysreqs": "cmake make libbz2-dev libicu-dev liblzma-dev\nlibuv1-dev libxml2-dev libssl-dev xz-utils zlib1g-dev", "Repository": "https://dylanbeeber.r-universe.dev", "Date/Publication": "2023-04-13 13:25:43 UTC", "RemoteUrl": "https://github.com/dylanbeeber/crisprdesignr", "RemoteRef": "HEAD", "RemoteSha": "00487e4987d2ce7e660bced05edace610f55b7f4", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-22 07:14:04 UTC", "User": "root" }, "Author": "Dylan Beeber [aut, cre],\nFrederic Chain [aut]", "Maintainer": "Dylan Beeber ", "MD5sum": "ff6bd3fc067993dbfc63e8e737ef2fc5", "_user": "dylanbeeber", "_type": "src", "_file": "crispRdesignR_1.1.7.tar.gz", "_fileid": "a4829e5fb11dcf1b062d7d5dee02b1defb80ba20e57de7a675096b10858f2d88", "_filesize": 1404283, "_sha256": 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