Package: crispRdesignR 1.1.7

crispRdesignR: Guide Sequence Design for CRISPR/Cas9

Designs guide sequences for CRISPR/Cas9 genome editing and provides information on sequence features pertinent to guide efficiency. Sequence features include annotated off-target predictions in a user-selected genome and a predicted efficiency score based on the model described in Doench et al. (2016) <doi:10.1038/nbt.3437>. Users are able to import additional genomes and genome annotation files to use when searching and annotating off-target hits. All guide sequences and off-target data can be generated through the 'R' console with sgRNA_Design() or through 'crispRdesignR's' user interface with crispRdesignRUI(). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and the associated protein Cas9 refer to a technique used in genome editing.

Authors:Dylan Beeber [aut, cre], Frederic Chain [aut]

crispRdesignR_1.1.7.tar.gz
crispRdesignR_1.1.7.zip(r-4.7-any)crispRdesignR_1.1.7.zip(r-4.6-any)crispRdesignR_1.1.7.zip(r-4.5-any)
crispRdesignR_1.1.7.tgz(r-4.6-any)crispRdesignR_1.1.7.tgz(r-4.5-any)
crispRdesignR_1.1.7.tar.gz(r-4.7-any)crispRdesignR_1.1.7.tar.gz(r-4.6-any)
crispRdesignR_1.1.7.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
crispRdesignR/json (API)

# Install 'crispRdesignR' in R:
install.packages('crispRdesignR', repos = c('https://dylanbeeber.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/dylanbeeber/crisprdesignr/issues

On CRAN:

Conda:

3.90 score 16 stars 8 scripts 506 downloads 1 mentions 6 exports 87 dependencies

Last updated from:00487e4987. Checks:7 NOTE, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develNOTE179
source / vignettesOK281
linux-releaseNOTE172
macos-releaseNOTE206
macos-oldrelNOTE182
windows-develNOTE156
windows-releaseNOTE171
windows-oldrelNOTE164
wasm-releaseOK162

Exports:crispRdesignRUIDoench_2016_processinggetofftargetdatagetsgRNAdatasgRNA_designsgRNA_design_function

Dependencies:askpassbase64encBHBiocBaseUtilsBiocGenericsBiocIOBiocParallelBiostringsbitopsbslibcachemcigarilloclicodetoolscommonmarkcpp11crayoncrosstalkcurldigestDTevaluatefastmapfontawesomeformatRfsfutile.loggerfutile.optionsgbmgenericsGenomeInfoDbGenomicAlignmentsGenomicRangesgluehighrhtmltoolshtmlwidgetshttpuvhttrIRangesjquerylibjsonliteknitrlambda.rlaterlatticelazyevallifecyclemagrittrMatrixmemoisemimeopensslotelpromisesR6rappdirsRcppRCurlrestfulrRhtslibrjsonrlangrmarkdownRsamtoolsrtracklayerS4VectorssassSeqinfoshinysnowsourcetoolsstringistringrsurvivalsystinytexUCSC.utilsvctrsvtreatwithrwraprxfunXMLxtableXVectoryaml